Giselle Pentón-Rol Selected Research

Phycocyanin

1/2023	The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome.
1/2022	Novel Insights into the Molecular Mechanisms Involved in the Neuroprotective Effects of C-Phycocyanin against Brain Ischemia in Rats.
4/2021	Phycocyanobilin is the molecule responsible for the nephroprotective action of phycocyanin in acute kidney injury caused by mercury.
1/2021	C-Phycocyanin-derived Phycocyanobilin as a Potential Nutraceutical Approach for Major Neurodegenerative Disorders and COVID-19- induced Damage to the Nervous System.
2/2018	Beneficial effects of oral administration of C-Phycocyanin and Phycocyanobilin in rodent models of experimental autoimmune encephalomyelitis.
1/2018	C-Phycocyanin and Phycocyanobilin as Remyelination Therapies for Enhancing Recovery in Multiple Sclerosis and Ischemic Stroke: A Preclinical Perspective.
3/2016	Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice.
10/2013	Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.
12/2012	C-Phycocyanin protects SH-SY5Y cells from oxidative injury, rat retina from transient ischemia and rat brain mitochondria from Ca2+/phosphate-induced impairment.
8/2011	C-Phycocyanin is neuroprotective against global cerebral ischemia/reperfusion injury in gerbils.

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Giselle Pentón-Rol Research Topics

Disease

4	Multiple Sclerosis 06/2022 - 03/2016
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2022 - 01/2011
3	Brain Ischemia (Cerebral Ischemia) 06/2022 - 08/2011
3	Ischemic Stroke 01/2020 - 12/2012
3	Stroke (Strokes) 01/2020 - 08/2011
2	Inflammation (Inflammations) 02/2023 - 01/2023
2	Neurodegenerative Diseases (Neurodegenerative Disease) 06/2022 - 01/2021
1	Experimental Arthritis 01/2023
1	Pain (Aches) 01/2023
1	Arthritis (Polyarthritis) 01/2023
1	Neuroinflammatory Diseases 01/2022
1	Demyelinating Diseases (Demyelinating Disease) 01/2022
1	Acute Kidney Injury (Acute Renal Failure) 04/2021
1	Brain Injuries (Brain Injury) 01/2020
1	Clinical Deterioration 03/2016
1	Ischemia 12/2012
1	Infarction (Infarctions) 08/2011
1	Acute Disease 08/2011
1	Reperfusion Injury 08/2011
1	Neuromyelitis Optica (Devic's Disease) 06/2009

Drug/Important Bio-Agent (IBA)

11	PhycocyaninIBA 01/2023 - 01/2011
9	phycocyanobilinIBA 01/2023 - 10/2013
4	Neuroprotective AgentsIBA 01/2022 - 08/2011
2	CytokinesIBA 01/2023 - 01/2022
2	AntioxidantsIBA 06/2022 - 03/2016
1	Fibronectins (Fibronectin)IBA 02/2023
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 02/2023
1	Proteins (Proteins, Gene)FDA Link 02/2023
1	VimentinIBA 02/2023
1	ProteomeIBA 01/2023
1	AntigensIBA 01/2023
1	methylated bovine serum albumin (MBSA)IBA 01/2023
1	Glutamic Acid (Glutamate)FDA Link 06/2022
1	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2022
1	Mercuric Chloride (Sublimate)IBA 04/2021
1	MercuryIBA 04/2021
1	Interleukin-17 (Interleukin 17)IBA 03/2016
1	TetrapyrrolesIBA 10/2013
1	Phosphates (Orthophosphate)IBA 12/2012
1	tert-ButylhydroperoxideIBA 12/2012
1	calcium phosphateIBA 12/2012
1	triphenyltetrazoliumIBA 08/2011
1	Malondialdehyde (Propanedial)IBA 08/2011
1	Interleukin-10 (Interleukin 10)IBA 06/2009
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2009

Therapy/Procedure

5	Therapeutics 06/2022 - 08/2011
1	Intradermal Injections 01/2023
1	Oral Administration 02/2018